"One-pot" access to dihydrofurans via tandem oxidative difunctionalization and ring contraction of aminopyrans.
نویسندگان
چکیده
An operationally simple and efficient protocol for the construction of dihydrofuran derivatives has been accomplished via a sequential addition of N-chlorosuccinimide and a base to 2-amino-4H-pyran derivatives in alcohol medium. The one-pot protocol proceeding via tandem oxidative difunctionalization and ring contraction provides an entirely new strategy for the construction of the dihydrofuran skeleton.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 12 25 شماره
صفحات -
تاریخ انتشار 2014